Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 8/20 | 0.50 |
| ▸ | BACE1 | P56817 | 8/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528687 | 0.92 | BACE1 (0.48) | CTSDBACE1BCHEALDH1A1F2 | |
| SCHEMBL6527345 | 0.87 | F2 (0.44) | CTSDBACE1BCHEF2 | |
| SCHEMBL6527142 | 0.87 | BACE1 (0.43) | CTSDBACE1BCHEF2 | |
| SCHEMBL5981669 | 0.87 | BACE1 (0.42) | CTSDBACE1BCHEF2 | |
| SCHEMBL6528253 | 0.86 | BACE1 (0.41) | CTSDBACE1BCHE | |
| SCHEMBL6529744 | 0.85 | ITGA4 (0.44) | CTSDBACE1 | |
| SCHEMBL8795519 | 0.83 | ALDH1A1 (0.40) | CTSDBACE1ALDH1A1F2 | |
| SCHEMBL2581377 | 0.80 | CTSD (0.46) | CTSDBACE1 | |
| SCHEMBL6529408 | 0.79 | F2 (0.41) | CTSDBACE1BCHEF2 | |
| Hydrochloric Acid SCHEMBL5928661 | 0.79 | CTSD (0.46) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3657002-B2 | — | — | 2005-06-08 | — | — | JP | claimed |
| WO-1994004492-A1 | HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1994-03-03 | — | — | WO | claimed |