SCHEMBL9873754

SCHEMBL9873754

NC(=O)c1c(-c2ccccc2)oc2ccccc2c1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.62
KMT2A Q03164 6/20 0.62
MEN1 O00255 5/20 0.62
LMNA P02545 4/20 0.62
CYP3A4 P08684 4/20 0.62
ALOX15 P16050 2/20 0.62
MAPK1 P28482 2/20 0.62
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
TP53 P04637 2/20 0.62
DDR2 Q16832 1/20 0.62
CA12 O43570 1/20 0.62
ABCB1 P08183 1/20 0.62
CALM1 P0DP23 1/20 0.62
AR P10275 1/20 0.62
PKM P14618 1/20 0.62
CYP1B1 Q16678 1/20 0.62
CA9 Q16790 1/20 0.62
RAB9A P51151 2/20 0.61
HSD17B10 Q99714 5/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31314572 0.89 RAB9A (0.70) KDM4EKMT2AMEN1LMNACYP3A4
SCHEMBL6527669 0.87 ALDH1A1 (0.69) KDM4EKMT2AMEN1LMNACYP3A4
SCHEMBL31398228 0.86 KMT2A (0.60) KDM4EKMT2AMEN1LMNACYP3A4
SCHEMBL26031862 0.84 KMT2A (0.62) KDM4EKMT2AMEN1LMNACYP3A4
SCHEMBL311250 0.84 KDM4E (0.62) KDM4EKMT2AMEN1LMNACYP3A4
SCHEMBL27784285 0.84 KMT2A (0.63) KDM4EKMT2AMEN1LMNACYP3A4
SCHEMBL1923200 0.82 KDM4E (0.59) KDM4EKMT2AMEN1LMNACYP3A4
SCHEMBL27913159 0.82 KMT2A (0.59) KDM4EKMT2AMEN1LMNACYP3A4
SCHEMBL23216981 0.80 KDM4E (0.56) KDM4EKMT2AMEN1LMNACYP3A4
SCHEMBL26031864 0.80 KMT2A (0.56) KDM4EKMT2AMEN1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61238783-A None JP disclosed
CN-118477069-B Use of (-) -wampee amide or compositions containing (-) -wampee amide for the manufacture of a medicament for the treatment of intestinal tract related diseases 济宁医学院 2024-12-10 CN disclosed
US-5013852-A Antiinflammatory KALI-CHEMIE PHARMA GMBH (DE) 1991-05-07 US disclosed
US-4886806-A ANTIINFLAMMATORY AGENTS KALI-CHEMIE PHARMA GMBH (DE) 1989-12-12 US disclosed
JP-S61238783-A FLAVONE CARBOXAMIDE DERIVATIVE HOKURIKU SEIYAKU CO LTD 1986-10-24 JP disclosed