SCHEMBL6528231

SCHEMBL6528231

Cc1ccc(C(C)c2ccc(C)o2)o1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.56
ALOX5 P09917 1/20 0.45
KDM1A O60341 1/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
CYP2C9 P11712 2/20 0.36
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
MAPT P10636 6/20 0.34
PKM P14618 2/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
POLB P06746 4/20 0.33
ALDH1A1 P00352 4/20 0.33
HPGD P15428 3/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2596762 0.82
SCHEMBL6528228 0.81 TDP1 (0.37) TDP1ALOX5KMT2AMEN1CYP2C9
SCHEMBL12779620 0.80 TDP1 (0.53) TDP1ALOX5KDM1AKMT2AMEN1
SCHEMBL12086682 0.80 TDP1 (0.53) TDP1ALOX5KDM1AKMT2AMEN1
SCHEMBL4983325 0.79 TDP1 (0.59) TDP1ALOX5KDM1AKMT2AMEN1
SCHEMBL11534755 0.78 TDP1 (0.50) TDP1ALOX5KDM1AKMT2AMEN1
SCHEMBL15963527 0.78
SCHEMBL12261721 0.78
SCHEMBL20962983 0.78 TDP1 (0.50) TDP1ALOX5KDM1AKMT2AMEN1
SCHEMBL13205324 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399318-A1 RENEWABLE OILS: COMPOSITION, PROCESS OF MAKING AND FORMULATION RiKarbon, Inc (US) 2023-12-14 US disclosed
WO-2022093748-A1 RENEWABLE OILS: COMPOSITION, PROCESS OF MAKING AND FORMULATION RIKARBON, INC. (US) 2022-05-05 WO disclosed
US-10618856-B2 Methods for producing cyclic and acyclic ketones THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-04-14 US disclosed
US-20190127292-A1 METHODS FOR PRODUCING CYCLIC AND ACYCLIC KETONES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-02 US disclosed
US-10207961-B2 Methods for producing cyclic and acyclic ketones THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-02-19 US disclosed
US-20180170824-A1 METHODS FOR PRODUCING CYCLIC AND ACYCLIC KETONES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-06-21 US disclosed
US-20180170824-A1 METHODS FOR PRODUCING CYCLIC AND ACYCLIC KETONES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-06-21 US disclosed
US-9199955-B2 Production of liquid fuels (sylvan-liquid-fuels) from 2-methylfuran CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2015-12-01 US disclosed
WO-2015148412-A2 METHODS FOR PRODUCING CYCLIC AND ACYCLIC KETONES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-10-01 WO disclosed
US-20120316372-A1 PRODUCTION OF LIQUID FUELS (SYLVAN-LIQUID-FUELS) FROM 2-METHYLFURAN CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2012-12-13 US disclosed
EP-2514802-A1 PRODUCTION OF LIQUID FUELS (SYLVAN LIQUID FUELS) FROM 2-METHYLFURAN Consejo Superior De Investigaciones Científicas (CSIC) (ES) 2012-10-24 EP disclosed
WO-2011070210-A1 PRODUCTION OF LIQUID FUELS (SYLVAN LIQUID FUELS) FROM 2-METHYLFURAN CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2011-06-16 WO disclosed
WO-2005097838-A1 DI-FURIL CONTAINING CATALYST AND PROCESS FOR PREPARATION OF TERMOELASTOPLASTIC POLYOLEFINS GAGIEVA, SVETLANA CHERMENOVNA (RU) 2005-10-20 WO disclosed
EP-0611301-A1 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1994-08-24 EP disclosed
EP-0611301-A4 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS. PROCTER & GAMBLE (US) 1993-03-01 EP disclosed
WO-1991016034-A1 CHELATOR COMPOSITIONS COMPRISING OXIME COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10618856-B2 Methods for producing cyclic and acyclic ketones PCCA, BCKDK, DECR2 TDP1 3518/4885ALOX5 106/4885KDM1A 1388/4885
US-20180170824-A1 METHODS FOR PRODUCING CYCLIC AND ACYCLIC KETONES PCCA, BCKDK, DECR2 TDP1 3518/4885ALOX5 106/4885KDM1A 1388/4885
US-10207961-B2 Methods for producing cyclic and acyclic ketones PCCA, BCKDK, DECR2 TDP1 3518/4885ALOX5 106/4885KDM1A 1388/4885
US-20190127292-A1 METHODS FOR PRODUCING CYCLIC AND ACYCLIC KETONES PCCA, BCKDK, DECR2 TDP1 3518/4885ALOX5 106/4885KDM1A 1388/4885
US-20230399318-A1 RENEWABLE OILS: COMPOSITION, PROCESS OF MAKING AND FORMULATION CBR1, CBR3, AKR1C3 TDP1 4464/4885ALOX5 131/4885KDM1A 375/4885
US-20120316372-A1 PRODUCTION OF LIQUID FUELS (SYLVAN-LIQUID-FUELS) FROM 2-METHYLFURAN ADH1A, ADH1C, ADH5 TDP1 3398/4885ALOX5 488/4885KDM1A 975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.