Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530208 | 0.83 | SYK (0.52) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL6532124 | 0.79 | NPC1 (0.60) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL8132914 | 0.77 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL3831190 | 0.77 | SMN1; SMN2 (0.55) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL6529620 | 0.75 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL592355 | 0.74 | ALDH1A1 (0.54) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL8116977 | 0.74 | TSHR (0.48) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL5861471 | 0.73 | MGLL (0.49) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL22808203 | 0.73 | TP53 (0.61) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL6530293 | 0.72 | SMN1; SMN2 (0.47) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |