Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506648 | 0.90 | PTPN11 (0.40) | S1PR1ATMGLASMN1; SMN2BACE1 | |
| SCHEMBL6529532 | 0.90 | S1PR1 (0.44) | S1PR1PPARGMMP12PTPN1PTPN6 | |
| SCHEMBL6532172 | 0.86 | LTA4H (0.42) | PTPN1PTPN6PTPN11 | |
| SCHEMBL6530514 | 0.85 | FDFT1 (0.41) | PPARGMMP12ACACBLMNA | |
| SCHEMBL6527581 | 0.84 | MMP12 (0.36) | S1PR1MMP12LMNA | |
| SCHEMBL6499997 | 0.83 | LMNA (0.36) | PPARGMMP12ACACBLMNA | |
| SCHEMBL6504727 | 0.83 | S1PR1 (0.45) | S1PR1ALDH1A1MMP12MEN1MAPT | |
| SCHEMBL6529689 | 0.82 | LMNA (0.37) | PPARGMMP12ACACBLMNAPTPN11 | |
| SCHEMBL6529753 | 0.82 | PPARG (0.34) | SMN1; SMN2PPARGMEN1LMNAKMT2A | |
| SCHEMBL6530111 | 0.81 | SRC (0.38) | KCNH2MMP12ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |