Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 4/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529214 | 0.85 | HPSE (0.60) | HPSEMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6325549 | 0.84 | ALDH1A1 (0.68) | HPSENT5EMEN1KMT2AALDH1A1 | |
| SCHEMBL6527955 | 0.81 | NPC1 (0.69) | HPSENT5EMEN1KMT2AALDH1A1 | |
| SCHEMBL5879596 | 0.78 | NPBWR1 (0.58) | HPSENT5EMEN1KMT2AALDH1A1 | |
| SCHEMBL24074249 | 0.76 | HPSE (0.58) | HPSEMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6482005 | 0.76 | ALDH1A1 (0.64) | HPSENT5EMEN1KMT2AALDH1A1 | |
| SCHEMBL6482012 | 0.76 | ALDH1A1 (0.64) | HPSENT5EMEN1KMT2AALDH1A1 | |
| SCHEMBL6533101 | 0.74 | NPC1 (0.56) | HPSEKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6529482 | 0.74 | HPSE (0.59) | HPSEKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL15443951 | 0.74 | MEN1 (0.79) | HPSENT5EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042496-A1 | (BENZIMIDAZOL-2-YL)-PHENYL-BENZYL-AMINE DERIVATIVES AND METHODS FOR INHIBITING HEPARANASE ACTIVITY | IMCLONE SYSTEMS INCORPORATED (US) | 2005-05-12 | — | — | WO | disclosed |