Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531139 | 0.94 | IDO1 (0.43) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1406150 | 0.77 | IDO1 (0.59) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4042268 | 0.75 | ICAM1 (0.36) | MEN1KMT2ACHUK | |
| SCHEMBL4909751 | 0.74 | TYMS (0.48) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3006431 | 0.71 | IDO1 (0.53) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5349617 | 0.71 | PTGS2 (0.62) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1406147 | 0.70 | ENPP2 (0.62) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4904629 | 0.70 | TYMS (0.46) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11985807 | 0.69 | ACHE (0.55) | IDO1ACHEMEN1KMT2ACHUK | |
| SCHEMBL4900956 | 0.69 | TYMS (0.43) | IDO1TYMSMEN1KMT2AENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121141-A1 | PYRROLOPYRIDINE DERIVATIVES AND USE THEREOF FOR TREATING DISEASES MEDIATED BY PROSTAGLANDIN D2 (PGD2) | OXAGEN LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |