Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20975374 | 0.85 | PDE10A (0.44) | PDE10ANCF1KDM4EALDH1A1HPGD | |
| SCHEMBL6529863 | 0.82 | NCF1 (0.47) | PDE10ANCF1KDM4EALDH1A1POLB | |
| SCHEMBL12495118 | 0.76 | ALDH1A1 (0.38) | PDE10ANCF1KDM4EALDH1A1HPGD | |
| SCHEMBL12495119 | 0.70 | HTR2C (0.41) | ALDH1A1 | |
| SCHEMBL7068901 | 0.69 | KDM4E (0.52) | KDM4EALDH1A1POLBKMT2AHPGD | |
| SCHEMBL20975373 | 0.68 | KDM4E (0.46) | NCF1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14349982 | 0.68 | CFTR (0.47) | KDM4EALDH1A1GAAKMT2AHPGD | |
| SCHEMBL20435731 | 0.67 | ABCC8 (0.62) | KDM4EALDH1A1POLBKMT2AACHE | |
| SCHEMBL21335097 | 0.67 | KDM4E (0.40) | KDM4EALDH1A1KMT2AACHEABCC8 | |
| SCHEMBL20440779 | 0.67 | SCN9A (0.47) | PDE10AKDM4EALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047259-A1 | 4-ANILINO-3-QUINOLINECARBONITRILES FOR THE TREATMENT OF CHRONIC MYELOGENOUS LEUKEMIA (CML) | WYETH (US) | 2005-05-26 | — | — | WO | disclosed |