Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529689 | 0.95 | LMNA (0.37) | CYP2D6PPARGPTPN11PTGESALOX5 | |
| SCHEMBL6530514 | 0.94 | FDFT1 (0.41) | NR1H4PPARGPTGESALOX5 | |
| SCHEMBL6530992 | 0.93 | LMNA (0.40) | PPARGPTPN11PTGESALOX5PPARA | |
| SCHEMBL6502426 | 0.88 | FFAR1 (0.42) | — | |
| SCHEMBL6527017 | 0.86 | MMP12 (0.40) | PPARGPPARA | |
| SCHEMBL6506648 | 0.85 | PTPN11 (0.40) | PTPN11MAPK1 | |
| SCHEMBL6528500 | 0.85 | CTSA (0.39) | NR1H4 | |
| SCHEMBL6528900 | 0.83 | MMP12 (0.39) | MAPK1 | |
| SCHEMBL6529141 | 0.82 | RARB (0.38) | PPARGPTPN11PTGESALOX5PPARA | |
| SCHEMBL6528235 | 0.82 | S1PR1 (0.46) | PPARGPTPN11PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |