Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529689 | 0.98 | LMNA (0.37) | LMNAPTPN11RARBP2RY10PTGES | |
| SCHEMBL6529916 | 0.93 | CYP2D6 (0.39) | PTPN11P2RY10PTGESALOX5PPARG | |
| SCHEMBL6530514 | 0.90 | FDFT1 (0.41) | LMNAPLA2G4BPTGESALOX5PPARG | |
| SCHEMBL6527017 | 0.90 | MMP12 (0.40) | RARBPPARGPPARAMMP12 | |
| SCHEMBL6528500 | 0.89 | CTSA (0.39) | MMP12 | |
| SCHEMBL6506648 | 0.88 | PTPN11 (0.40) | PTPN11 | |
| SCHEMBL6502426 | 0.86 | FFAR1 (0.42) | — | |
| SCHEMBL6528900 | 0.85 | MMP12 (0.39) | LMNAMMP12 | |
| SCHEMBL6502328 | 0.84 | RARB (0.42) | LMNARARBPTGESALOX5PPARG | |
| SCHEMBL6529230 | 0.84 | LMNA (0.40) | LMNARARBMMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |