Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 8/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504727 | 0.93 | S1PR1 (0.45) | MMP12S1PR1S1PR2RARBRARA | |
| SCHEMBL6530992 | 0.90 | LMNA (0.40) | MMP12RARBPPARGPPARA | |
| SCHEMBL6529689 | 0.89 | LMNA (0.37) | MMP12RARBRARAPPARGPPARA | |
| SCHEMBL6528900 | 0.87 | MMP12 (0.39) | MMP12 | |
| SCHEMBL6530514 | 0.87 | FDFT1 (0.41) | MMP12PPARG | |
| SCHEMBL6529916 | 0.86 | CYP2D6 (0.39) | PPARGPPARA | |
| SCHEMBL6506648 | 0.85 | PTPN11 (0.40) | S1PR1ALDH1A1MAPT | |
| SCHEMBL6528500 | 0.83 | CTSA (0.39) | MMP12MAPT | |
| SCHEMBL6532172 | 0.83 | LTA4H (0.42) | — | |
| SCHEMBL6502426 | 0.82 | FFAR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |