Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530992 | 0.98 | LMNA (0.40) | LMNAPTGESALOX5PPARGPPARA | |
| SCHEMBL6529916 | 0.95 | CYP2D6 (0.39) | PTGESALOX5PPARGPPARACYP2D6 | |
| SCHEMBL6530514 | 0.92 | FDFT1 (0.41) | LMNAPTGESALOX5PPARGMMP12 | |
| SCHEMBL6528500 | 0.90 | CTSA (0.39) | MMP12ACACBFFAR1 | |
| SCHEMBL6527017 | 0.89 | MMP12 (0.40) | PPARGPPARAMMP12RARARARB | |
| SCHEMBL6502426 | 0.88 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL6528900 | 0.87 | MMP12 (0.39) | LMNAMMP12FFAR1 | |
| SCHEMBL6506648 | 0.87 | PTPN11 (0.40) | PTPN11 | |
| SCHEMBL6502328 | 0.86 | RARB (0.42) | LMNAPTGESALOX5PPARGPPARA | |
| SCHEMBL6529532 | 0.82 | S1PR1 (0.44) | PTGESALOX5PPARGMMP12RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |