SCHEMBL6529935

SCHEMBL6529935

CC(=O)N(c1ccc2ccc3cccc4ccc1c2c34)C(C)(C(=O)O)c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 3/20 0.35
HSD17B10 Q99714 3/20 0.35
MEN1 O00255 2/20 0.35
CYP1A2 P05177 2/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6529936 1.00 ALDH1A1 (0.40) ALDH1A1HPGDKDM4EMAPTKMT2A
SCHEMBL15023884 0.72 ALDH1A1 (0.44) ALDH1A1HPGDKDM4EMAPTKMT2A
SCHEMBL5527765 0.72 ALDH1A1 (0.44) ALDH1A1HPGDKDM4EMAPTKMT2A
SCHEMBL29291615 0.68 ALDH1A1 (0.44) ALDH1A1HPGDKDM4EMAPTKMT2A
SCHEMBL6508561 0.68 ALDH1A1 (0.43) ALDH1A1HPGDKDM4EMAPTKMT2A
SCHEMBL2396985 0.67 ALDH1A1 (0.50) ALDH1A1HPGDKDM4EMAPTKMT2A
SCHEMBL571692 0.67 ALDH1A1 (0.54) ALDH1A1HPGDKDM4EMAPTKMT2A
Formaldehyde SCHEMBL28437274 0.66 ALDH1A1 (0.48) ALDH1A1HPGDKDM4EMAPTKMT2A
SCHEMBL9749674 0.65 ALDH1A1 (0.43) ALDH1A1HPGDKDM4EMAPTKMT2A
Pyrene SCHEMBL6033008 0.64 ALDH1A1 (0.61) ALDH1A1HPGDKDM4EMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050124535-A1 Cyclic peptide nanotube structures for molecular scale electronic and photonic devices WORCESTER POLYTECHNIC INSTITUTE 2005-06-09 US disclosed
US-6902720-B2 Cyclic peptide structures for molecular scale electronic and photonic devices WORCESTER POLYTECHNIC INSTITUTE (US) 2005-06-07 US disclosed
US-6893716-B2 Non-covalent assembly of multilayer thin film supramolecular structures WORCESTER POLYTECHNIC INSTITUTE (US) 2005-05-17 US disclosed
US-20040110009-A1 Non-covalent assembly of multilayer thin film supramolecular structures WORCESTER POLYTECHNIC INSTITUTE 2004-06-10 US disclosed
US-20030144185-A1 Cyclic peptide structures for molecular scale electronic and photonic devices WORCESTER POLYTECHNIC INSTITUTE 2003-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050124535-A1 Cyclic peptide nanotube structures for molecular scale electronic and photonic devices NPPA, NGF, QRFPR ALDH1A1 3561/4885HPGD 4371/4885KDM4E 4591/4885
US-20030144185-A1 Cyclic peptide structures for molecular scale electronic and photonic devices VIP, NPPA, NGLY1 ALDH1A1 3571/4885HPGD 4343/4885KDM4E 4770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.