Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508934 | 0.79 | KMT2A (0.33) | PPARGALDH1A1MAPTKMT2APAX8 | |
| SCHEMBL6533898 | 0.76 | ALDH1A1 (0.41) | ALDH1A1POLBMAPTTP53KMT2A | |
| SCHEMBL6527308 | 0.66 | CYP4F2 (0.39) | ALDH1A1 | |
| SCHEMBL1683548 | 0.64 | ELANE (0.62) | ALDH1A1TDP1RAB9AMAPTKMT2A | |
| SCHEMBL6509824 | 0.64 | CYP4F2 (0.34) | PPARGRXFP1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL6528870 | 0.63 | NOTUM (0.39) | ALDH1A1NPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL4068968 | 0.63 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL27485334 | 0.63 | ELANE (0.55) | ALDH1A1TDP1RAB9AMAPTKMT2A | |
| SCHEMBL2785015 | 0.62 | MEN1 (0.47) | PPARGALDH1A1NPC1TDP1NPSR1 | |
| SCHEMBL6528105 | 0.61 | PPARA (0.40) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056536-A1 | ANTIDIABETIC AGENTS WHICH EXHIBIT ACTIVITY AGAINST PPAR | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-23 | — | — | WO | disclosed |