Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509824 | 0.83 | CYP4F2 (0.34) | KMT2ACLCN2ALDH1A1MEN1MYC | |
| SCHEMBL6533898 | 0.80 | ALDH1A1 (0.41) | KMT2AMAPTHDAC6ALDH1A1MEN1 | |
| SCHEMBL6530164 | 0.79 | PPARG (0.34) | KMT2AMAPTPAX8ELANEALDH1A1 | |
| SCHEMBL6530940 | 0.74 | KMT2A (0.39) | KMT2AMAPTALDH1A1MEN1HTT | |
| SCHEMBL6528744 | 0.69 | THRB (0.36) | KMT2AMAPTCLCN2ALDH1A1 | |
| SCHEMBL6527238 | 0.67 | NPSR1 (0.45) | MAPTCLCN2ALDH1A1MAPK1 | |
| SCHEMBL6528870 | 0.66 | NOTUM (0.39) | KMT2AMAPTCLCN2ALDH1A1MEN1 | |
| SCHEMBL1683548 | 0.66 | ELANE (0.62) | KMT2AMAPTPAX8ELANEALDH1A1 | |
| SCHEMBL27485334 | 0.64 | ELANE (0.55) | KMT2AMAPTPAX8ELANEALDH1A1 | |
| SCHEMBL2785015 | 0.64 | MEN1 (0.47) | KMT2ACLCN2ALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056536-A1 | ANTIDIABETIC AGENTS WHICH EXHIBIT ACTIVITY AGAINST PPAR | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-23 | — | — | WO | disclosed |