Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508934 | 0.80 | KMT2A (0.33) | ALDH1A1MAPK1MAPTHDAC6MEN1 | |
| SCHEMBL6530164 | 0.76 | PPARG (0.34) | ALDH1A1MAPTTP53POLBKMT2A | |
| SCHEMBL6533895 | 0.71 | PPARG (0.50) | — | |
| SCHEMBL6528870 | 0.71 | NOTUM (0.39) | ALDH1A1MAPTTP53POLBKDM4E | |
| SCHEMBL6527238 | 0.70 | NPSR1 (0.45) | ALDH1A1LMNAMAPK1MAPTPOLB | |
| SCHEMBL6528744 | 0.69 | THRB (0.36) | ALDH1A1LMNAMAPTTP53POLB | |
| SCHEMBL6530940 | 0.64 | KMT2A (0.39) | ALDH1A1LMNAMAPTTP53POLB | |
| SCHEMBL6509824 | 0.64 | CYP4F2 (0.34) | ALDH1A1POLBMEN1KMT2AGAA | |
| SCHEMBL6675390 | 0.64 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPK1GFERMAPT | |
| SCHEMBL1683548 | 0.63 | ELANE (0.62) | ALDH1A1LMNAMAPK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056536-A1 | ANTIDIABETIC AGENTS WHICH EXHIBIT ACTIVITY AGAINST PPAR | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-23 | — | — | WO | claimed |