Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.44 |
| ▸ | IDH1 | O75874 | 12/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530894 | 0.92 | OGFRL1 (0.46) | HDAC6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6527860 | 0.91 | BRD4 (0.46) | HDAC6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6532288 | 0.84 | ACSL1 (0.41) | OPRM1OPRD1OPRK1OPRL1OGFRL1 | |
| SCHEMBL6528391 | 0.83 | OPRM1 (0.41) | HDAC6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6530892 | 0.83 | L3MBTL1 (0.58) | HDAC6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6528355 | 0.83 | IDH1 (0.41) | OPRM1OPRD1OPRK1OPRL1OGFRL1 | |
| SCHEMBL6533044 | 0.82 | ALDH1A1 (0.46) | OPRM1OPRD1OPRK1OPRL1OGFRL1 | |
| SCHEMBL6528295 | 0.82 | LMNA (0.44) | OPRM1OPRD1OPRK1OPRL1OGFRL1 | |
| SCHEMBL6528420 | 0.82 | OGFRL1 (0.47) | HDAC6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6531083 | 0.80 | L3MBTL1 (0.39) | HDAC6OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019186-A1 | 2-AMINOBENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF HIV/AIDS | BAYER HEALTHCARE AG (DE) | 2005-03-03 | — | — | WO | disclosed |