Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.41 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.40 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.40 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532520 | 0.91 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAANPC1RAB9A | |
| SCHEMBL6527860 | 0.87 | BRD4 (0.46) | L3MBTL1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6528391 | 0.85 | OPRM1 (0.41) | L3MBTL1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6528355 | 0.85 | IDH1 (0.41) | ALDH1A1KDM4EGAAL3MBTL1OPRM1 | |
| SCHEMBL6528295 | 0.84 | LMNA (0.44) | GAANPC1RAB9AOPRM1OPRD1 | |
| SCHEMBL6532516 | 0.83 | L3MBTL1 (0.55) | ALDH1A1KDM4EGAANPC1RAB9A | |
| SCHEMBL6532288 | 0.82 | ACSL1 (0.41) | L3MBTL1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6530267 | 0.82 | HDAC6 (0.46) | L3MBTL1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6531083 | 0.82 | L3MBTL1 (0.39) | L3MBTL1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6529996 | 0.81 | L3MBTL1 (0.40) | L3MBTL1OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019186-A1 | 2-AMINOBENZIMIDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF HIV/AIDS | BAYER HEALTHCARE AG (DE) | 2005-03-03 | — | — | WO | disclosed |