Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134270 | 0.78 | POLB (0.47) | TSHRLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6277714 | 0.78 | POLB (0.47) | TSHRLMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL4494684 | 0.78 | L3MBTL1 (0.48) | L3MBTL1TSHRUSP2HTTLMNA | |
| SCHEMBL25299662 | 0.70 | TSHR (0.57) | L3MBTL1TSHRUSP2KDM4ESMN1; SMN2 | |
| SCHEMBL25306793 | 0.70 | L3MBTL1 (0.64) | L3MBTL1TSHRUSP2HTTKDM4E | |
| SCHEMBL12130555 | 0.68 | LMNA (0.44) | TSHRUSP2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11826133 | 0.67 | ALDH1A1 (0.38) | L3MBTL1TSHRUSP2LMNAKDM4E | |
| SCHEMBL1927517 | 0.64 | LTA4H (0.49) | L3MBTL1TSHRKDM4EALDH1A1ALOX12 | |
| SCHEMBL1927983 | 0.64 | LTA4H (0.49) | L3MBTL1TSHRKDM4EALDH1A1ALOX12 | |
| SCHEMBL24723410 | 0.64 | MGLL (0.49) | TSHRUSP2LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004098525-A9 | USES OF ION CHANNEL MODULATING COMPOUNDS | CARDIOME PHARMA CORP (CA) | 2005-01-20 | — | — | WO | disclosed |