Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 9/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504395 | 0.94 | PPARA (0.37) | SMN1; SMN2PPARAPPARDPPARG | |
| SCHEMBL6531507 | 0.94 | PARP1 (0.36) | SMN1; SMN2NPC1RAB9APPARAADORA2A | |
| SCHEMBL6494741 | 0.93 | PPARA (0.39) | PPARAADORA2AADORA1PPARDPPARG | |
| SCHEMBL6498709 | 0.90 | CDK2 (0.34) | NPC1PPARAPPARDTP53 | |
| Trifluoroacetic Acid SCHEMBL6505042 | 0.89 | PPARA (0.42) | SMN1; SMN2NPC1RAB9APPARAPPARD | |
| SCHEMBL6503597 | 0.88 | KDM4E (0.36) | NPC1RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL6505593 | 0.87 | ADORA2A (0.35) | NPC1RAB9APPARAADORA2AADORA1 | |
| SCHEMBL6495822 | 0.86 | SHMT1 (0.39) | KDM4EHPGDKMT2A | |
| SCHEMBL6499174 | 0.86 | ADORA1 (0.38) | SMN1; SMN2NPC1RAB9AADORA2AADORA1 | |
| Trifluoroacetic Acid SCHEMBL6531504 | 0.83 | PPARA (0.40) | SMN1; SMN2PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |