Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17261304 | 0.81 | HIF1A (0.38) | DNM1HIF1AHTR2AHRH1LMNA | |
| SCHEMBL2450923 | 0.78 | HTR2A (0.40) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL6531597 | 0.77 | — | — | |
| SCHEMBL19050995 | 0.76 | — | — | |
| SCHEMBL17143495 | 0.76 | CHRNB2 (0.36) | LMNASMN1; SMN2SLC6A2HTT | |
| SCHEMBL18050404 | 0.76 | DNM1 (0.35) | DNM1HIF1ALMNASMN1; SMN2SLC6A2 | |
| SCHEMBL17261305 | 0.76 | L3MBTL1 (0.36) | DNM1HIF1ALMNASMN1; SMN2SLC6A2 | |
| SCHEMBL23714469 | 0.75 | PRMT3 (0.42) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL476608 | 0.74 | DNM1 (0.40) | DNM1HIF1AHTR2AHRH1LMNA | |
| SCHEMBL2586284 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403712-B1 | DRY SPINNING USING POLY(N-VINYL-2-PYRROLIDONE) WITH ELASTOMER SEGMENTED POLYURETHANES BASED ON METHYLENEBIS (4-ISOCYANATOBENZENE), A POLYTETRAMETHYLENE GLYCOL, ETHYLENE GLYCOL, 1,3-PROPANE DIOL, AND 2-METHYLBUTANEDIOL | DUPONT TORAY CO. LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1025294-B1 | PROCESS FOR THE MANUFACTURE OF SPANDEX AND THE SPANDEX MADE THEREBY | DU PONT TORAY CO LTD (JP) | 2002-05-08 | — | — | EP | disclosed |
| US-4812565-A | ANTIHISTAMINE INTERMEDIATES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-14 | — | — | US | disclosed |
| US-4810795-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| US-4727152-A | Intermediates useful in the preparation of fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof | A. H. ROBINS COMPANY, INC. (US) | 1988-02-23 | — | — | US | disclosed |
| US-4705853-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INC. (US) | 1987-11-10 | — | — | US | disclosed |
| US-4642343-A | ANTIHISTAMINES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-02-10 | — | — | US | disclosed |
| US-4604388-A | Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof in a method of counteracting histamine | A. H. ROBINS COMPANY, INCORPORATED (US) | 1986-08-05 | — | — | US | disclosed |
| US-4592866-A | Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof | A. H. ROBINS COMPANY, INC. (US) | 1986-06-03 | — | — | US | disclosed |