Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pivalate SCHEMBL29574099 | 1.00 | BRD4 (0.33) | BRD4CCL2LMNAALDH1A1SMN1; SMN2 | |
| Benzoic Acid SCHEMBL7262963 | 0.82 | CA2 (0.46) | BRD4CCL2LMNAALDH1A1SMN1; SMN2 | |
| Fluoride Ion SCHEMBL1130940 | 0.81 | DRD2 (0.39) | BRD4CCL2DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8665926 | 0.81 | DRD2 (0.39) | BRD4CCL2DRD2DRD4 | |
| Pivalate SCHEMBL3910093 | 0.76 | LMNA (0.36) | LMNAALDH1A1SMN1; SMN2TDP1HBB | |
| Pivalate SCHEMBL29574882 | 0.73 | MEN1 (0.34) | BRD4CCL2LMNAALDH1A1TDP1 | |
| Pivalate SCHEMBL650158 | 0.73 | MEN1 (0.34) | BRD4CCL2LMNAALDH1A1TDP1 | |
| Pivalate SCHEMBL7596893 | 0.70 | ALDH1A1 (0.34) | BRD4CCL2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3312303 | 0.66 | BRD4 (0.39) | BRD4CCL2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7006425 | 0.65 | BRD4 (0.38) | BRD4CCL2LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0961784-B1 | IMPROVED CONTROL OF SOLUTION CATALYST DROPLET SIZE WITH AN EFFERVESCENT SPRAY NOZZLE | UNION CARBIDE CHEM PLASTIC (US) | 2002-10-23 | — | — | EP | claimed |
| EP-2018389-B1 | HAFNIUM COMPLEXES OF CARBAZOLYL SUBSTITUTED IMIDAZOLE LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-03-09 | — | — | EP | disclosed |
| EP-2018390-B1 | ORTHO-METALLATED HAFNIUM COMPLEXES OF IMIDAZOLE LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-03-09 | — | — | EP | disclosed |
| EP-2021381-B1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-9181368-B2 | High activity, low molecular weight olefin polymerization process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140066585-A1 | HIGH ACTIVITY, LOW MOLECULAR WEIGHT OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-03-06 | — | — | US | disclosed |
| US-8604145-B2 | High activity, low molecular weight olefin polymerization process | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-12-10 | — | — | US | disclosed |
| US-8580976-B2 | Process for preparing A 2-substituted benzofuran-3-yl borate ester | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-11-12 | — | — | US | disclosed |
| US-20130102795-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102789-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-25 | — | — | US | disclosed |
| EP-1054025-A1 | Method for controlling molecular weight and molecular weight distribution in polymers produced using a single site catalyst | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-11-22 | — | — | EP | disclosed |
| EP-1054024-A1 | Inert particulate material passivation for single-site catalyst in EPDM production | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-11-22 | — | — | EP | disclosed |
| US-6136747-A | SOLID ZIEGLER-NATTA CATALYST; A LIQUID SINGLE SITE CATALYST; AND AT LEAST ONE ACTIVATING COCATALYST IS PROVIDED. POLYMERS HAVING A BROAD OR BIMODAL MOLECULAR WEIGHT DISTRIBUTION MAY BE MADE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-10-24 | — | — | US | disclosed |
| WO-2000002930-A1 | A CATALYST COMPOSITION AND METHODS FOR ITS PREPARATION AND USE IN A POLYMERIZATION PROCESS | UNIVATION TECHNOLOGIES LLC (US) | 2000-01-20 | — | — | WO | disclosed |
| WO-2000002931-A1 | A CATALYST COMPOSITION AND METHODS FOR ITS PREPARATION AND USE IN A POLYMERIZATION PROCESS | UNIVATION TECHNOLOGIES LLC (US) | 2000-01-20 | — | — | WO | disclosed |
| EP-0965601-A1 | Mixed catalyst composition for the production of olefin polymers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0952996-A1 | METHOD OF CONTROLLING OLEFIN POLYMERIZATION CATALYST COMPOSITION ACTIVITY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0942009-A2 | Reduced sheeting in single-site and single-site like polymerization by employing a chromium containing compound | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (a Delaware corporation) (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5912202-A | CONTACTING OUTSIDE OF POLYMERIZATION REACTOR A SINGLE SITE CATALYST PRECURSOR WITH AN ACTIVATING COCATALYST BEFORE, DURING, OR AFTER CONTACTING THE SINGLE SITE CATALYST PRECURSOR WITH A WEAKLY COORDINATING ELECTRON DONOR SUCH AS 1-HEXENE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| WO-1998030608-A1 | METHOD OF CONTROLLING OLEFIN POLYMERIZATION CATALYST COMPOSITION ACTIVITY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102795-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | HACL2, MIA3, HAO2 | BRD4 1093/4885CCL2 591/4885LMNA 3120/4885 |
| US-20130102789-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | HACL2, MIA3, HAO2 | BRD4 1093/4885CCL2 591/4885LMNA 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.