Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22902147 | 0.85 | NOTUM (0.44) | NPBWR1MCHR1NOTUMMTORESRRA | |
| SCHEMBL12194623 | 0.83 | ACACB (0.39) | DRD4HTR2CDRD2DRD3KCNH2 | |
| SCHEMBL6533713 | 0.81 | NOTUM (0.51) | NPBWR1NOTUMDRD4HTR2CDRD2 | |
| SCHEMBL6533912 | 0.81 | DRD4 (0.55) | NOTUMDRD4HTR2CDRD2DRD3 | |
| SCHEMBL6530604 | 0.80 | LMNA (0.41) | DRD4HTR2CDRD2DRD3KCNH2 | |
| SCHEMBL22902068 | 0.79 | NOTUM (0.50) | NOTUMMTORESRRAEGLN1 | |
| SCHEMBL28980400 | 0.78 | MEN1 (0.41) | DRD4HTR2CDRD2DRD3KCNH2 | |
| SCHEMBL15180418 | 0.78 | DRD4 (0.52) | NOTUMMTORDRD4HTR2CDRD2 | |
| SCHEMBL2412911 | 0.78 | GAA (0.58) | NOTUMDRD4HTR2CDRD2DRD3 | |
| SCHEMBL1930732 | 0.77 | GABRA1 (0.43) | DRD4HTR2CDRD2DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |