Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530604 | 0.84 | LMNA (0.41) | MAPTRAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16062853 | 0.84 | RXRA (0.47) | NOTUMMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2412259 | 0.82 | ALDH1A1 (0.41) | NOTUMMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL28980400 | 0.82 | MEN1 (0.41) | MAPTNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL15180418 | 0.82 | DRD4 (0.52) | NOTUMMAPTRAB9AALDH1A1HPGD | |
| SCHEMBL25365261 | 0.82 | NOTUM (0.44) | NOTUMMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL6533912 | 0.82 | DRD4 (0.55) | NOTUMMAPTNPC1RAB9AKDM4E | |
| SCHEMBL2412911 | 0.81 | GAA (0.58) | NOTUMMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL6532804 | 0.81 | NPBWR1 (0.43) | NOTUMDRD4DRD2NPBWR1HTR2C | |
| SCHEMBL1930732 | 0.81 | GABRA1 (0.43) | MAPTRAB9AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |