Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025286 | 0.90 | BCL2L1 (0.35) | BCL2L1MAPTPOLBTDP1CA1 | |
| SCHEMBL6025611 | 0.81 | BCL2L1 (0.35) | BCL2L1CA2CA4DOT1L | |
| SCHEMBL6530524 | 0.70 | KMT2A (0.41) | BCL2L1MAPTPOLBTDP1CA1 | |
| SCHEMBL6025032 | 0.69 | KMT2A (0.41) | BCL2L1MAPTPOLBTDP1CA1 | |
| SCHEMBL6532196 | 0.63 | LMNA (0.39) | MAPTPOLBCA1CA2CA12 | |
| SCHEMBL6025517 | 0.62 | KMT2A (0.44) | BCL2L1MAPTPOLBTDP1CA1 | |
| SCHEMBL6530526 | 0.60 | KMT2A (0.51) | MAPTCA1CA2ALDH1A1LMNA | |
| SCHEMBL2943101 | 0.60 | MAPT (0.55) | BCL2L1MAPTPOLBTDP1SMN1; SMN2 | |
| SCHEMBL6470754 | 0.59 | CA2 (0.45) | CA1CA2CA12CA9CA7 | |
| SCHEMBL1131516 | 0.59 | ALDH1A1 (0.45) | POLBTDP1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |