SCHEMBL253445

SCHEMBL253445

C=CC(=O)OCCCOc1ccc(C(=O)OC2C(C)=Cc3cccc4cccc2c34)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.38
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 4/20 0.34
TDP1 Q9NUW8 2/20 0.34
HEXA P06865 1/20 0.34
HEXB P07686 1/20 0.34
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPN6 P29350 1/20 0.33
PTPN11 Q06124 1/20 0.33
MAPT P10636 4/20 0.32
RAB9A P51151 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TBXAS1 P24557 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28979493 0.97 HTT (0.39) THRBHTTL3MBTL1TDP1HEXA
SCHEMBL21859029 0.90 TSHR (0.31) THRBHPGDTSHRALDH1A1
SCHEMBL13777704 0.72 L3MBTL1 (0.54) THRBL3MBTL1TDP1HPGDTSHR
SCHEMBL17036979 0.71 THRB (0.58) THRBHTTL3MBTL1TDP1HPGD
SCHEMBL17341715 0.71 THRB (0.49) THRBHTTL3MBTL1TDP1HPGD
SCHEMBL16379489 0.71 THRB (0.49) THRBHTTL3MBTL1TDP1HPGD
SCHEMBL10040451 0.71 PTPN2 (0.44) THRBHTTL3MBTL1HPGDTSHR
SCHEMBL5319700 0.71 THRB (0.49) THRBHTTL3MBTL1TDP1HPGD
SCHEMBL12141874 0.71 MAPT (0.64) THRBHTTL3MBTL1TDP1HPGD
SCHEMBL10065788 0.70 THRB (0.59) THRBHTTL3MBTL1TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022049424-A1 METHOD FOR PRODUCING VARIABLE-SHAPE MICROPATTERNED POLYMER TACTILE MATERIAL USING ELECTRIC FIELD TECHNIQUE 한국과학기술원 2022-03-10 WO claimed
US-8574689-B2 O-plate having excellent durability and itegrated polarizing plate comprising the same LG CHEM, LTD. (KR) 2013-11-05 US claimed
US-20090117293-A1 O-Plate Having Excellent Durability and Itegrated Polarizing Plate Comprising the Same LG CHEM, LTD. (KR) 2009-05-07 US claimed
US-20240084183-A1 THERMAL CIRCUITS BUILT IN LIQUID CRYSTAL ELASTOMERS IMPRESSIO INC. 2024-03-14 US disclosed
CN-111373311-B Display device comprising photochromic-dichroic compound and dichroic compound PPG工业俄亥俄公司 2023-04-04 CN disclosed
CN-115349006-A Mesogenic compounds 光学转变有限公司 2022-11-15 CN disclosed
WO-2022049424-A1 METHOD FOR PRODUCING VARIABLE-SHAPE MICROPATTERNED POLYMER TACTILE MATERIAL USING ELECTRIC FIELD TECHNIQUE 한국과학기술원 2022-03-10 WO disclosed
US-10914987-B2 Complex and optical element KYOTO UNIVERSITY (JP) 2021-02-09 US disclosed
US-20200241336-A1 COMPLEX AND OPTICAL ELEMENT KYOTO UNIVERSITY (JP) 2020-07-30 US disclosed
CN-111373311-A Display device comprising photochromic-dichroic compound and dichroic compound PPG工业俄亥俄公司 2020-07-03 CN disclosed
EP-3368927-A1 OPTICAL ARTICLE WITH GRADIENT LIGHT INFLUENCING PROPERTIES AND METHOD OF MAKING THE SAME Transitions Optical, Inc. (US) 2018-09-05 EP disclosed
US-8431039-B2 Mesogenic stabilizers TRANSITIONS OPTICAL, INC. (US) 2013-04-30 US disclosed
US-20120002141-A1 MESOGENIC STABILIZERS TRANSITIONS OPTICAL, INC. (US) 2012-01-05 US disclosed
CN-101726785-B Retardation film and method for forming the same IND TECH RES INST 2011-10-26 CN disclosed
US-7858669-B2 Composition for alignment film having excellent adhesiveness LG CHEM, LTD. (KR) 2010-12-28 US disclosed
CN-101726785-A Retardation film and method for forming the same IND TECH RES INST 2010-06-09 CN disclosed
US-20090312453-A1 Composition for Alignment Film Having Excellent Adhesiveness LG CHEM, LTD. (KR) 2009-12-17 US disclosed
US-20090117293-A1 O-Plate Having Excellent Durability and Itegrated Polarizing Plate Comprising the Same LG CHEM, LTD. (KR) 2009-05-07 US disclosed
WO-2008060109-A1 COMPOSITION FOR ALIGNMENT FILM HAVING EXCELLENT ADHESIVENESS LG CHEM, LTD. (KR) 2008-05-22 WO disclosed
WO-2008060108-A1 O-PLATE HAVING EXCELLENT DURABILITY AND INTEGRATED POLARIZING PLATE COMPRISING THE SAME LG CHEM, LTD. (KR) 2008-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120002141-A1 MESOGENIC STABILIZERS BMI1, METTL14, PYM1 THRB 4510/4885HTT 743/4885L3MBTL1 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.