Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.48 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790481 | 0.85 | MTNR1A (0.54) | GHSRMTNR1AMTNR1BFAAHP2RX7 | |
| SCHEMBL3195898 | 0.83 | GHSR (0.49) | GHSRMTNR1AMTNR1BFAAHP2RX7 | |
| SCHEMBL8588823 | 0.81 | MTNR1A (0.56) | GHSRMTNR1AMTNR1BFAAHP2RX7 | |
| SCHEMBL9526679 | 0.81 | FAAH (0.48) | GHSRMTNR1AMTNR1BFAAHP2RX7 | |
| SCHEMBL5608206 | 0.80 | FAAH (0.53) | GHSRMTNR1AMTNR1BFAAHP2RX7 | |
| SCHEMBL6427539 | 0.80 | FAAH (0.53) | GHSRMTNR1AMTNR1BFAAHP2RX7 | |
| SCHEMBL367535 | 0.80 | FAAH (0.53) | GHSRMTNR1AMTNR1BFAAHP2RX7 | |
| SCHEMBL6534296 | 0.79 | GHSR (0.49) | GHSRMTNR1AMTNR1BFAAHP2RX7 | |
| Hydrochloric Acid SCHEMBL9266537 | 0.79 | ANPEP (0.53) | GHSRMTNR1AMTNR1BFAAHP2RX7 | |
| SCHEMBL6534185 | 0.77 | FAAH (0.53) | GHSRMTNR1AMTNR1BFAAHP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088818-B1 | Quinolin-4-yl derivatives | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |