Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | CASP3 | P42574 | 3/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751167 | 1.00 | NPC1 (0.71) | NPC1RAB9AKDM4EMAPTCASP3 | |
| Sulfuric Acid SCHEMBL22418993 | 0.92 | CA12 (0.63) | NPC1RAB9AKDM4EMAPTCASP3 | |
| SCHEMBL5053299 | 0.90 | NPC1 (0.87) | NPC1RAB9AKDM4EMAPTCASP3 | |
| SCHEMBL28416625 | 0.88 | NPC1 (0.83) | NPC1RAB9AKDM4EMAPTCASP3 | |
| SCHEMBL25455013 | 0.84 | CDK5 (0.76) | NPC1RAB9AKDM4EMAPTCASP3 | |
| SCHEMBL10997076 | 0.84 | NPC1 (0.92) | NPC1RAB9AKDM4EMAPTCASP3 | |
| 2-Phenyl-1H-Indole SCHEMBL341378 | 0.84 | NPC1 (1.00) | NPC1RAB9AKDM4EMAPTCASP3 | |
| 2-Phenyl-1H-Indole SCHEMBL29363616 | 0.84 | NPC1 (1.00) | NPC1RAB9AKDM4EMAPTCASP3 | |
| SCHEMBL4258578 | 0.82 | CDK5 (0.71) | NPC1RAB9AKDM4EMAPTMEN1 | |
| Fluoride SCHEMBL27588167 | 0.82 | NPC1 (0.88) | NPC1RAB9AKDM4EMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522128-C | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2009-08-05 | — | — | CN | claimed |
| US-20240116923-A1 | USE OF INDOLE, 6- AND 7-AZAINDOLE DERIVATIVES AS INHIBITORS OF FERROPTOSIS REGULATED CELL DEATH | SEABELIFE (FR) | 2024-04-11 | — | — | US | disclosed |
| CN-117529317-A | Use of indole, 6-and 7-azaindole derivatives as inhibitors of iron death-mediated cell death | 海洋生命公司 | 2024-02-06 | — | — | CN | disclosed |
| EP-4281070-A1 | USE OF INDOLE, 6- AND 7-AZAINDOLE DERIVATIVES AS INHIBITORS OF FERROPTOSIS REGULATED CELL DEATH | Seabelife (FR) | 2023-11-29 | — | — | EP | disclosed |
| CN-116916912-A | Protein toxicity of sulfated C19 steroid hormone for treatment and/or prevention of protein aggregation disease | 帕布罗·德奥拉韦德大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-116801877-A | Epididymal sulfate and/or steroid sulfatase inhibitors for treating or improving age-related cognitive impairment | 帕布罗·德奥拉韦德大学 | 2023-09-22 | — | — | CN | disclosed |
| WO-2022157392-A1 | USE OF INDOLE, 6- AND 7-AZAINDOLE DERIVATIVES AS INHIBITORS OF FERROPTOSIS REGULATED CELL DEATH | SEABELIFE (FR) | 2022-07-28 | — | — | WO | disclosed |
| CN-112601521-A | Composition for treating and/or preventing protein aggregation diseases | 帕布罗·德奥拉韦德大学 | 2021-04-02 | — | — | CN | disclosed |
| CN-105531321-B | Polycarbonate-based toughness thermal conductive polymer composite and purposes | 沙特基础全球技术有限公司 | 2017-08-01 | — | — | CN | disclosed |
| US-9701626-B2 | Antagonists of the glucagon receptor | METABASIS THERAPEUTICS, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-4661511-A | ANTITUMOR AGENTS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1987-04-28 | — | — | US | disclosed |
| US-4543360-A | ANTIESTROGENS, ANTITUMOR | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-09-24 | — | — | US | disclosed |
| US-4543360-A | ANTIESTROGENS, ANTITUMOR | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-09-24 | — | — | US | disclosed |
| US-4543360-A | ANTIESTROGENS, ANTITUMOR | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-09-24 | — | — | US | disclosed |
| US-4256626-A | 2-BENZIMIDAZOLYL-, 2-BENZOTHIAZOLYL-, OR 2-INDOLYL-PHENYL DERIVATIVES LINKED TO A 2-HYDROXYBENZOPHENONE | EASTMAN KODAK COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| US-4187213-A | CONTAINING BENZOTHIAZOLE, BENZIMIDAZOLE, BENZOTHIAZOLE OR INDOLE RING AND PIPERIDINE RING | EASTMAN KODAK COMPANY (US) | 1980-02-05 | — | — | US | disclosed |
| US-4174321-A | POLYMERIC MOLDING MATERIALS | EASTMAN KODAK COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4127501-A | BENZOXAZOLE, BENZOTHIAZOLE, BENZIMIDAZOLE, BENZOTRIAZOLE OR INDOLE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4115348-A | DEGRADATION INHIBITORS | EASTMAN KODAK COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4057530-A | STABILIZERS FOR VINYL CHLORIDE POLYMERS | LABAZ (FR) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116923-A1 | USE OF INDOLE, 6- AND 7-AZAINDOLE DERIVATIVES AS INHIBITORS OF FERROPTOSIS REGULATED CELL DEATH | AIFM2, SLC40A1, FECH | NPC1 1324/4885RAB9A 2293/4885KDM4E 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.