SCHEMBL6535222

SCHEMBL6535222

COc1ccc(-c2oc3cccc(O)c3c(=O)c2O)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.72
CYP1A1 P04798 1/20 0.72
CYP1A2 P05177 1/20 0.72
ABCB1 P08183 1/20 0.72
CYP1B1 Q16678 1/20 0.72
FTO Q9C0B1 1/20 0.72
CYP3A4 P08684 6/20 0.69
KDM4E B2RXH2 5/20 0.69
MAPT P10636 5/20 0.69
HSD17B10 Q99714 4/20 0.69
MEN1 O00255 4/20 0.69
KMT2A Q03164 4/20 0.69
TP53 P04637 3/20 0.69
HPGD P15428 3/20 0.69
LMNA P02545 2/20 0.69
MAPK1 P28482 2/20 0.69
USP2 O75604 1/20 0.69
ALOX15 P16050 1/20 0.69
ALDH1A1 P00352 2/20 0.69
ABCG2 Q9UNQ0 3/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31126017 0.88 MAOA (0.64) MAOACYP1A1CYP1A2ABCB1CYP1B1
SCHEMBL9665959 0.86 MAPT (0.73) MAOACYP1A1CYP1A2ABCB1CYP1B1
SCHEMBL748643 0.85 MAOA (0.90) MAOACYP1A1CYP1A2ABCB1CYP1B1
SCHEMBL8749579 0.84 MAOA (0.70) MAOACYP1A1CYP1A2ABCB1CYP1B1
SCHEMBL29582121 0.84 KDM4E (0.59) MAOACYP1A1CYP1A2ABCB1CYP1B1
SCHEMBL10335363 0.84 MEN1 (0.79) MAOACYP1A1CYP1A2ABCB1CYP1B1
Kaempferide SCHEMBL29371282 0.84 CYP1A2 (1.00) MAOACYP1A1CYP1A2ABCB1CYP1B1
Kaempferide SCHEMBL426774 0.84 CYP1A2 (1.00) MAOACYP1A1CYP1A2ABCB1CYP1B1
SCHEMBL12455834 0.83 CYP1A1 (0.79) MAOACYP1A1CYP1A2ABCB1CYP1B1
SCHEMBL14764339 0.83 MEN1 (0.76) MAOACYP1A1CYP1A2ABCB1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113616801-A Preparation method and application of antiseptic and antibacterial preparation containing Scutellariae radix extract 南京益唯森生物科技有限公司 2021-11-09 CN disclosed
EP-1047420-A4 MODULATION OF HAIR GROWTH GILLETTE CO (US) 2004-04-14 EP disclosed
EP-1047420-A1 MODULATION OF HAIR GROWTH HANDELMAN, Joseph H. (US) 2000-11-02 EP disclosed
WO-1999036067-A1 MODULATION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-07-22 WO disclosed