Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.70 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | CASP1 | P29466 | 2/20 | 0.63 |
| ▸ | CASP7 | P55210 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.62 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316302 | 0.87 | MAPT (0.63) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL28747747 | 0.87 | ABCG2 (0.72) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL9665640 | 0.86 | MAOA (0.74) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL6535222 | 0.84 | MAOA (0.72) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL28563029 | 0.84 | MAPT (0.67) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Betuletol SCHEMBL29400938 | 0.84 | TUBB4A (0.86) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL28430943 | 0.84 | TP53 (0.60) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL748643 | 0.83 | MAOA (0.90) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| SCHEMBL20798544 | 0.83 | MEN1 (0.68) | MAOACYP1A1CYP1A2CYP1B1ABCB1 | |
| Kaempferide SCHEMBL29371282 | 0.82 | CYP1A2 (1.00) | MAOACYP1A1CYP1A2CYP1B1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230322-A1 | ADDRESSING INJECTION SITE REACTIONS ASSOCIATED WITH THE ADMINISTRATION OF ELAMIPRETIDE | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-11-30 | — | — | WO | claimed |
| CN-113801084-B | Polymethoxy flavone extracted from orange vinegar fermentation substrate sludge, extraction method and application | 三峡大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-114317630-A | Preparation method of diosmetin | 成都欧康医药股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-111100104-B | Preparation method of diosmetin | 陕西嘉禾药业有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-110279758-B | Peony leaf dry powder, preparation method thereof and application of peony leaf dry powder as xanthine oxidase inhibitor | 陕西凤丹正元生物科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113801084-A | Polymethoxyflavone extracted from orange vinegar fermentation substrate sludge, and extraction method and application thereof | 三峡大学 | 2021-12-17 | — | — | CN | disclosed |
| CN-113018294-A | Application of diosmetin | 西北农林科技大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-109180627-B | Semi-synthesis method of diosmetin | 陕西嘉禾生物科技股份有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-111100104-A | Preparation method of diosmetin | 陕西嘉禾药业有限公司 | 2020-05-05 | — | — | CN | disclosed |
| US-20190203240-A1 | METHODS FOR THE PRODUCTION OF RHAMNOSYLATED FLAVONOIDS | UNIV HAMBURG (DE) | 2019-07-04 | — | — | US | disclosed |
| US-20190100549-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | UNIVERSITAET HAMBURG (DE) | 2019-04-04 | — | — | US | disclosed |
| EP-3402788-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | Universität Hamburg (DE) | 2018-11-21 | — | — | EP | disclosed |
| EP-3402893-A1 | METHODS FOR THE PRODUCTION OF RHAMNOSYLATED FLAVONOIDS | Universität Hamburg (DE) | 2018-11-21 | — | — | EP | disclosed |
| WO-2017121855-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | UNIVERSITÄT HAMBURG (DE) | 2017-07-20 | — | — | WO | disclosed |
| WO-2017121863-A1 | METHODS FOR THE PRODUCTION OF RHAMNOSYLATED FLAVONOIDS | UNIVERSITÄT HAMBURG (DE) | 2017-07-20 | — | — | WO | disclosed |
| EP-0420232-B1 | Water soluble derivatives of glycoside bioflavonoids, processes for their preparation and related pharmaceutical compositions | EUROP PHARMACY SRL (IT) | 1997-03-26 | — | — | EP | disclosed |
| EP-0420232-A2 | Water soluble derivatives of glycoside bioflavonoids, processes for their preparation and related pharmaceutical compositions | EUROPEAN PHARMACY Srl (IT) | 1991-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190100549-A1 | FLAVONOIDE-TYPE COMPOUNDS BEARING AN O-RHAMNOSYL RESIDUE | LRAT, TYR, CUTA | MAOA 62/4885CYP1A1 127/4885CYP1A2 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.