SCHEMBL6535261

SCHEMBL6535261

Cc1cccc(Nc2c(C)ccc3c2C2(OC3=O)c3ccccc3Oc3ccccc32)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.43
NPSR1 Q6W5P4 3/20 0.43
MAPT P10636 8/20 0.39
FTO Q9C0B1 4/20 0.39
TDP1 Q9NUW8 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
HPGD P15428 2/20 0.39
HTT P42858 2/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
SMAD3 P84022 1/20 0.39
PRMT1 Q99873 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
ADORA2A P29274 1/20 0.38
POLB P06746 3/20 0.37
ALOX12 P18054 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2186537 0.91 FTO (0.40) LMNANPSR1MAPTFTOTDP1
SCHEMBL7772047 0.89 MAPT (0.38) LMNANPSR1MAPTFTOTDP1
SCHEMBL10634017 0.87 LMNA (0.41) LMNANPSR1MAPTFTOTDP1
SCHEMBL10884503 0.86 LMNA (0.40) LMNANPSR1MAPTFTOTDP1
SCHEMBL10637360 0.82 RAPGEF4 (0.39) LMNANPSR1MAPTFTOTDP1
SCHEMBL28247843 0.81 FTO (0.55) LMNANPSR1MAPTFTOTDP1
SCHEMBL387083 0.80 NPSR1 (0.38) LMNANPSR1MAPTTDP1MEN1
SCHEMBL10885744 0.80 FTO (0.39) LMNANPSR1MAPTFTOTDP1
SCHEMBL6535406 0.80 NPSR1 (0.38) LMNANPSR1MAPTTDP1MEN1
SCHEMBL10358663 0.79 MAPT (0.43) LMNANPSR1MAPTFTOTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1161504-A4 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2004-12-01 EP claimed
EP-1161504-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION Esco Company (US) 2001-12-12 EP claimed
WO-2000049096-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2000-08-24 WO claimed
WO-2012160084-A1 IMPROVED NEAR INFRARED ABSORBERS TETRA LAVAL HOLDINGS & FINANCE S.A. (CH) 2012-11-29 WO disclosed
EP-1161504-A4 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2004-12-01 EP disclosed
EP-1161504-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION Esco Company (US) 2001-12-12 EP disclosed
WO-2000049096-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2000-08-24 WO disclosed