SCHEMBL7772047

SCHEMBL7772047

Cc1ccc(Nc2c(C)ccc3c2C2(OC3=O)c3ccccc3Oc3ccccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.38
HTT P42858 6/20 0.38
FTO Q9C0B1 5/20 0.38
HPGD P15428 4/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
RECQL P46063 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
BLM P54132 2/20 0.38
CYP2C19 P33261 1/20 0.38
SMAD3 P84022 1/20 0.38
PRMT1 Q99873 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
LMNA P02545 7/20 0.37
NPSR1 Q6W5P4 2/20 0.37
POLB P06746 4/20 0.36
ALOX12 P18054 2/20 0.36
GPR55 Q9Y2T6 1/20 0.36
ALDH1A1 P00352 5/20 0.35
SMN1; SMN2 Q16637 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2186537 0.93 FTO (0.40) MAPTHTTFTOHPGDMEN1
SCHEMBL6535261 0.89 LMNA (0.43) MAPTHTTFTOHPGDMEN1
SCHEMBL10634017 0.86 LMNA (0.41) MAPTHTTFTOHPGDMEN1
SCHEMBL10884503 0.85 LMNA (0.40) MAPTHTTFTOHPGDMEN1
SCHEMBL10637360 0.84 RAPGEF4 (0.39) MAPTHTTFTOHPGDMEN1
SCHEMBL10885744 0.82 FTO (0.39) MAPTHTTFTOHPGDMEN1
SCHEMBL10358663 0.81 MAPT (0.43) MAPTHTTFTOHPGDMEN1
SCHEMBL28247843 0.81 FTO (0.55) MAPTHTTFTOHPGDMEN1
SCHEMBL10633830 0.81 PTGS2 (0.40) MAPTHTTFTOHPGDMEN1
SCHEMBL10803492 0.80 MAOA (0.37) MAPTHTTFTOHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115579-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION Ciba SC Holding AG (CH) 2001-07-18 EP disclosed
WO-2000012318-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed
EP-0083075-B1 COLOUR DEVELOPING SHEET FOR A PRESSURE-SENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1986-08-13 EP disclosed