SCHEMBL2186537

SCHEMBL2186537

Cc1ccc2c(c1Nc1ccccc1)C1(OC2=O)c2ccccc2Oc2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 0.40
MAPT P10636 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HTT P42858 3/20 0.40
CYP2C19 P33261 3/20 0.40
HPGD P15428 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
SMAD3 P84022 1/20 0.40
PRMT1 Q99873 1/20 0.40
ACE2 Q9BYF1 1/20 0.40
CXCR2 P25025 1/20 0.39
LMNA P02545 4/20 0.37
NPSR1 Q6W5P4 4/20 0.37
ALOX12 P18054 2/20 0.37
POLB P06746 2/20 0.37
GPR55 Q9Y2T6 1/20 0.37
CYP2C9 P11712 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7772047 0.93 MAPT (0.38) FTOMAPTMEN1KMT2AHTT
SCHEMBL6535261 0.91 LMNA (0.43) FTOMAPTMEN1KMT2AHTT
SCHEMBL28247843 0.88 FTO (0.55) FTOMAPTMEN1KMT2AHTT
SCHEMBL10637360 0.86 RAPGEF4 (0.39) FTOMAPTMEN1KMT2AHTT
SCHEMBL10634017 0.84 LMNA (0.41) FTOMAPTMEN1KMT2AHTT
SCHEMBL10885744 0.84 FTO (0.39) FTOMAPTMEN1KMT2AHTT
SCHEMBL10358663 0.83 MAPT (0.43) FTOMAPTMEN1KMT2AHTT
SCHEMBL10633830 0.83 PTGS2 (0.40) FTOMAPTMEN1KMT2AHTT
SCHEMBL10884503 0.83 LMNA (0.40) FTOMAPTMEN1KMT2AHTT
SCHEMBL11118957 0.81 CXCR2 (0.30) CXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024078971-A1 HEAT-SENSITIVE RECORDING MATERIAL KOEHLER INNOVATION & TECHNOLOGY GMBH (DE) 2024-04-18 WO claimed
EP-4297978-A1 COMPOSITIONS AND METHODS FOR SENSITIZING HEAT MEDIA Solenis Technologies Cayman, L.P. (CH) 2024-01-03 EP claimed
EP-4200139-A1 HEAT-SENSITIVE RECORDING MATERIAL, AND HEAT-SENSITIVE RECORDING LAYER AND COATING COMPOSITION FOR PRODUCING SAME, CORRESPONDING USES AND METHOD Mitsubishi HiTec Paper Europe GmbH (DE) 2023-06-28 EP claimed
EP-1161504-A4 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2004-12-01 EP claimed
EP-1161504-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION Esco Company (US) 2001-12-12 EP claimed
WO-2000049096-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2000-08-24 WO claimed
JP-58059891-A None JP disclosed
JP-58071192-A None JP disclosed
JP-5301460-A None JP disclosed
EP-4297978-A1 COMPOSITIONS AND METHODS FOR SENSITIZING HEAT MEDIA Solenis Technologies Cayman, L.P. (CH) 2024-01-03 EP disclosed
CN-111556812-A Thermosensitive recording medium, thermosensitive recording medium production method and product 株式会社理光 2020-08-18 CN disclosed
CN-110271310-A Thermal recording material and its manufacturing method 卡西欧计算机株式会社 2019-09-24 CN disclosed
EP-2349734-A1 AQUEOUS LASER-SENSITIVE COMPOSITION FOR MARKING SUBSTRATES DataLase Ltd (GB) 2011-08-03 EP disclosed
WO-1993001940-A1 HEAT SENSITIVE RECORDING PAPER WITH IMAGE STABILITY NASHUA CORPORATION (US) 1993-02-04 WO disclosed
WO-1992001566-A1 THERMAL LATENT IMAGE MATERIAL AND METHOD OF PRODUCING AND DEVELOPING THE SAME NASHUA CORPORATION (US) 1992-02-06 WO disclosed
EP-0464828-A1 Heat sensitive recording material NIPPON SHOKUBAI CO., LTD. (JP) 1992-01-08 EP disclosed
EP-0349194-A2 Heat-sensitive record material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-01-03 EP disclosed
EP-0283032-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1988-09-21 EP disclosed
JP-S5871192-A HEAT-SENSITIVE RECORDING PAPER JUJO PAPER CO LTD 1983-04-27 JP disclosed
JP-S5859891-A COLOR FORMING COMPOSITION SHIN NISSO KAKO CO LTD 1983-04-09 JP disclosed