Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059032 | 0.83 | COMT (0.49) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL30613483 | 0.79 | HTT (0.56) | CYP1A2ALDH1A1TP53MAPTLMNA | |
| SCHEMBL21241436 | 0.76 | NR2E1 (0.41) | TAS2R14CYP1A2ALDH1A1IDH1MAPT | |
| SCHEMBL3305340 | 0.74 | KDM4E (0.59) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL92819 | 0.74 | KDM4E (0.57) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL10690095 | 0.73 | GABRA2 (0.41) | ALDH1A1HPGDMAPTLMNAF10 | |
| SCHEMBL6535778 | 0.73 | HSP90AA1 (0.52) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL17491390 | 0.71 | CYP11B1 (0.38) | ALDH1A1KDM4ELMNAF10NOTUM | |
| SCHEMBL3349831 | 0.71 | ALDH1A1 (0.36) | CYP1A2ALDH1A1KDM4EHPGDBLM | |
| SCHEMBL6535629 | 0.71 | TSHR (0.50) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261338-A4 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR INC (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1261338-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | Cymar, Inc. (US) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001062253-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR, INC. (US) | 2001-08-30 | — | — | WO | disclosed |