Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965393 | 0.87 | KDM4E (0.43) | KDM4EGAAMAPTALDH1A1MAPK1 | |
| SCHEMBL6535756 | 0.79 | TDP1 (0.39) | GAAMAPTALDH1A1MAPK1TSHR | |
| SCHEMBL6535758 | 0.77 | ALDH1A1 (0.37) | GAAMAPTALDH1A1TSHRNPC1 | |
| SCHEMBL6535654 | 0.75 | TDP1 (0.48) | KDM4EGAAMAPTALDH1A1MAPK1 | |
| SCHEMBL6535648 | 0.73 | POLB (0.43) | KDM4EMAPTALDH1A1TSHRMAOB | |
| SCHEMBL6535506 | 0.70 | GAA (0.33) | GAAALDH1A1TSHRNPC1 | |
| SCHEMBL159592 | 0.70 | MAPT (0.83) | KDM4EGAAMAPTALDH1A1MAPK1 | |
| SCHEMBL30197402 | 0.70 | MAPT (0.83) | KDM4EGAAMAPTALDH1A1MAPK1 | |
| SCHEMBL1131997 | 0.68 | MAPT (0.80) | KDM4EGAAMAPTALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL2475806 | 0.68 | MAPT (0.88) | KDM4EGAAMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359887-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6673932-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| EP-1359887-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20030131422-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2003-07-17 | — | — | US | disclosed |
| WO-2002058658-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G - CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030131422-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, COX5A | KDM4E 3202/4885GAA 4653/4885MAPT 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.