Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.45 |
| ▸ | ME1 | P48163 | 1/20 | 0.45 |
| ▸ | ME3 | Q16798 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536192 | 0.86 | RXRA (0.42) | NR5A1ALDH1A1MEN1NPC1GAA | |
| SCHEMBL6536638 | 0.86 | PLA2G4B (0.43) | ALDH1A1MEN1NPC1GAAMAPT | |
| SCHEMBL8385525 | 0.85 | MEN1 (0.59) | NR5A1LTA4HALDH1A1MEN1NPC1 | |
| SCHEMBL14088619 | 0.82 | NPC1 (0.41) | NR5A1ALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL11354421 | 0.82 | THRA (0.54) | NR5A1LTA4HALDH1A1MEN1NPC1 | |
| SCHEMBL11357497 | 0.82 | THRA (0.54) | NR5A1LTA4HALDH1A1MEN1NPC1 | |
| SCHEMBL8143543 | 0.82 | THRA (0.54) | NR5A1LTA4HALDH1A1MEN1NPC1 | |
| SCHEMBL4894161 | 0.81 | NPC1 (0.53) | LTA4HALDH1A1MEN1NPC1GAA | |
| SCHEMBL6536488 | 0.81 | PDK2 (0.50) | NR5A1LTA4HALDH1A1MEN1NPC1 | |
| SCHEMBL4942353 | 0.78 | PTGS2 (0.54) | ALDH1A1MEN1MAPTKMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824709-B2 | A LIQUID CRYSTAL COMPOUND OR LIQUID CRYSTAL POLYMERS, CONTAINING ACRYLATE OR METHACRYLATE FLUORENE GROUP; LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030203128-A1 | Fluorene derivatives and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |