Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536140 | 0.86 | NR5A1 (0.52) | PLA2G4BPTPN11NPC1LMNACYP3A4 | |
| SCHEMBL6536493 | 0.85 | MAPT (0.56) | PTPN11NPC1THRBMEN1ALDH1A1 | |
| SCHEMBL6536395 | 0.82 | PDK2 (0.47) | PLA2G4BPTPN11S1PR1S1PR3S1PR4 | |
| SCHEMBL14088414 | 0.80 | TSHR (0.49) | PLA2G4BPTPN11S1PR1S1PR3THRB | |
| SCHEMBL6536192 | 0.80 | RXRA (0.42) | PTPN11NPC1THRBHTR2ATHRA | |
| SCHEMBL14088619 | 0.79 | NPC1 (0.41) | PLA2G4BPTPN11NPC1LMNACYP3A4 | |
| SCHEMBL11357497 | 0.78 | THRA (0.54) | PTPN11NPC1THRBTHRAMEN1 | |
| SCHEMBL11354421 | 0.78 | THRA (0.54) | PTPN11NPC1THRBTHRAMEN1 | |
| SCHEMBL8143543 | 0.78 | THRA (0.54) | PTPN11NPC1THRBTHRAMEN1 | |
| SCHEMBL6536073 | 0.78 | THRB (0.47) | PTPN11THRBHTR2AALOX5THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824709-B2 | A LIQUID CRYSTAL COMPOUND OR LIQUID CRYSTAL POLYMERS, CONTAINING ACRYLATE OR METHACRYLATE FLUORENE GROUP; LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030203128-A1 | Fluorene derivatives and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |