Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 8/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536140 | 0.86 | NR5A1 (0.52) | PDK2MEN1NPC1ALDH1A1GAA | |
| SCHEMBL6536073 | 0.80 | THRB (0.47) | RXRAHTR2ATHRATHRBPTPN11 | |
| SCHEMBL6536638 | 0.80 | PLA2G4B (0.43) | MEN1NPC1ALDH1A1GAAMAPT | |
| SCHEMBL11357497 | 0.78 | THRA (0.54) | PDK2MEN1NPC1ALDH1A1GAA | |
| SCHEMBL8143543 | 0.78 | THRA (0.54) | PDK2MEN1NPC1ALDH1A1GAA | |
| SCHEMBL25797424 | 0.78 | NR5A1 (0.56) | MCL1PDK2MEN1NPC1ALDH1A1 | |
| SCHEMBL11354421 | 0.78 | THRA (0.54) | PDK2MEN1NPC1ALDH1A1GAA | |
| SCHEMBL9222413 | 0.77 | NR5A1 (0.59) | MCL1CNR2NR5A1 | |
| SCHEMBL26547916 | 0.77 | NR5A1 (0.59) | MCL1CNR2NR5A1 | |
| SCHEMBL25797434 | 0.77 | NR5A1 (0.59) | MCL1CNR2NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824709-B2 | A LIQUID CRYSTAL COMPOUND OR LIQUID CRYSTAL POLYMERS, CONTAINING ACRYLATE OR METHACRYLATE FLUORENE GROUP; LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030203128-A1 | Fluorene derivatives and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |