Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 9/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088435 | 0.84 | ALOX5 (0.38) | THRBFAAHPTGESALOX5PPARG | |
| SCHEMBL14088416 | 0.82 | THRB (0.51) | THRBTHRAPPARGHTR2APTPN11 | |
| SCHEMBL14088445 | 0.81 | THRB (0.50) | THRBHTR2APTPN11 | |
| SCHEMBL6536192 | 0.80 | RXRA (0.42) | THRBTHRAHTR2APTPN11RXRA | |
| SCHEMBL14088443 | 0.80 | THRB (0.47) | THRBTHRAHTR2APTPN11 | |
| SCHEMBL6536638 | 0.78 | PLA2G4B (0.43) | THRBTHRAALOX5HTR2APTPN11 | |
| SCHEMBL14088409 | 0.78 | THRB (0.46) | THRBHTR2APTPN11 | |
| SCHEMBL14088437 | 0.77 | THRB (0.62) | THRBTHRAHTR2A | |
| SCHEMBL14088440 | 0.77 | RARB (0.46) | THRBHTR2APTPN11 | |
| SCHEMBL14075603 | 0.77 | THRB (0.46) | THRBTHRAHTR2APTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824709-B2 | A LIQUID CRYSTAL COMPOUND OR LIQUID CRYSTAL POLYMERS, CONTAINING ACRYLATE OR METHACRYLATE FLUORENE GROUP; LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030203128-A1 | Fluorene derivatives and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |