Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | TFEB | P19484 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150272 | 0.84 | AR (0.55) | HTTMAPTLMNANFE2L2TFEB | |
| SCHEMBL28708188 | 0.80 | MIF (0.54) | HTTPTGER4PTGER3PTGER2PTGER1 | |
| Coumarinic Acid Methyl Ether SCHEMBL5277765 | 0.80 | NFE2L2 (0.64) | HTTGAASMN1; SMN2MAPTLMNA | |
| SCHEMBL8651474 | 0.79 | HTT (0.74) | HTTPTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL8651473 | 0.79 | HTT (0.74) | HTTPTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL10614570 | 0.77 | NFE2L2 (0.59) | NFE2L2 | |
| Coumarinic Acid Methyl Ether SCHEMBL714857 | 0.77 | NFE2L2 (0.77) | HTTGAASMN1; SMN2MAPTLMNA | |
| Coumarinic Acid Methyl Ether SCHEMBL79060 | 0.77 | NFE2L2 (0.77) | HTTGAASMN1; SMN2MAPTLMNA | |
| Coumarinic Acid Methyl Ether SCHEMBL83064 | 0.77 | NFE2L2 (0.77) | HTTGAASMN1; SMN2MAPTLMNA | |
| Coumarinic Acid Methyl Ether SCHEMBL29369917 | 0.77 | NFE2L2 (0.77) | HTTGAASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377837-A4 | ARRAY-BASED BIOMOLECULE ANALYSIS | PROTEOME SYSTEMS LTD (AU) | 2004-04-14 | — | — | EP | disclosed |
| EP-1377837-A1 | ARRAY-BASED BIOMOLECULE ANALYSIS | Proteome Systems Ltd. (AU) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002075321-A1 | ARRAY-BASED BIOMOLECULE ANALYSIS | PROTEOME SYSTEMS LTD (AU) | 2002-09-26 | — | — | WO | disclosed |