SCHEMBL6536738

SCHEMBL6536738

c1ccc(C2([C]3SCCS3)SCCS2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.34
MAOA P21397 3/20 0.34
BACE1 P56817 1/20 0.33
CNR1 P21554 1/20 0.32
OPRM1 P35372 2/20 0.31
OPRK1 P41145 1/20 0.31
OPRL1 P41146 1/20 0.31
CYP26A1 O43174 1/20 0.31
RXRA P19793 1/20 0.31
CYP26B1 Q9NR63 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
CYP2B6 P20813 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
PRCP P42785 1/20 0.31
SLC6A3 Q01959 1/20 0.31
GRIN1 Q05586 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11616948 0.84 CYP26A1 (0.39) MAOBMAOACNR1OPRM1OPRK1
SCHEMBL8121006 0.75 RXRA (0.41) MAOBMAOAOPRM1OPRK1OPRL1
SCHEMBL12436887 0.72 OPRM1 (0.46) MAOBMAOACNR1OPRM1OPRK1
SCHEMBL7938624 0.72 ALDH1A1 (0.40) CNR1OPRM1OPRK1OPRL1CYP26A1
SCHEMBL9792504 0.72 NOTUM (0.39) BACE1CNR1CYP26A1RXRACYP26B1
SCHEMBL7935992 0.72 TSHR (0.40) MAOBMAOABACE1OPRM1OPRK1
SCHEMBL10635037 0.69 BACE1 (0.34) MAOBMAOABACE1CYP26A1RXRA
SCHEMBL12436889 0.68 OPRM1 (0.54) MAOBMAOABACE1OPRM1OPRK1
SCHEMBL9792691 0.68 ALDH1A1 (0.39) OPRM1OPRK1OPRL1ALDH1A1SLC6A2
SCHEMBL5751200 0.68 RXRA (0.61) CYP26A1RXRACYP26B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686140-B2 Silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2004-02-03 US disclosed