Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616948 | 0.87 | CYP26A1 (0.39) | CYP26A1RXRACYP26B1KMT2AOPRM1 | |
| SCHEMBL7938624 | 0.79 | ALDH1A1 (0.40) | KDM1ARCOR1CYP26A1RXRACYP26B1 | |
| SCHEMBL12436887 | 0.79 | OPRM1 (0.46) | TSHRCYP1A2CYP26A1RXRACYP26B1 | |
| SCHEMBL8121006 | 0.78 | RXRA (0.41) | RXRAOPRM1OPRK1OPRL1MAOA | |
| SCHEMBL9792504 | 0.75 | NOTUM (0.39) | CYP26A1RXRACYP26B1KMT2AKDM4E | |
| SCHEMBL5751200 | 0.75 | RXRA (0.61) | TSHRCYP26A1RXRACYP26B1 | |
| SCHEMBL12436889 | 0.75 | OPRM1 (0.54) | CYP26A1RXRACYP26B1KMT2AMAPK1 | |
| SCHEMBL9792690 | 0.75 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL6536738 | 0.72 | MAOB (0.34) | CYP26A1RXRACYP26B1OPRM1OPRK1 | |
| SCHEMBL18123696 | 0.72 | RXRA (0.39) | KDM1ARCOR1CYP26A1RXRACYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730566-B1 | SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | F2 CHEMICALS LTD (GB) | 2001-09-19 | — | — | EP | disclosed |
| EP-0730566-A1 | SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-09-11 | — | — | EP | disclosed |
| WO-1996003357-A1 | SELECTIVELY FLUORINATED ORGANIC COMPOUNDS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-02-08 | — | — | WO | disclosed |