Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434618 | 0.84 | HSD11B1 (0.44) | L3MBTL1HSD11B1KMT2AALDH1A1NPC1 | |
| SCHEMBL7445271 | 0.84 | HSD11B1 (0.41) | L3MBTL1HSD11B1KMT2AALDH1A1NPC1 | |
| SCHEMBL7472982 | 0.80 | HSD11B1 (0.38) | L3MBTL1HSD11B1KMT2AALDH1A1NPC1 | |
| SCHEMBL8955444 | 0.76 | KMT2A (0.40) | L3MBTL1HSD11B1KMT2AALDH1A1NPC1 | |
| SCHEMBL7442282 | 0.74 | TAAR1 (0.43) | L3MBTL1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7448856 | 0.74 | ROCK2 (0.36) | L3MBTL1HSD11B1KMT2AALDH1A1NPC1 | |
| SCHEMBL8955449 | 0.71 | L3MBTL1 (0.38) | L3MBTL1HSD11B1KMT2AALDH1A1NPC1 | |
| SCHEMBL6654051 | 0.70 | HSD11B1 (0.56) | L3MBTL1HSD11B1KMT2AALDH1A1NPC1 | |
| SCHEMBL6654048 | 0.70 | HSD11B1 (0.56) | L3MBTL1HSD11B1KMT2AALDH1A1NPC1 | |
| SCHEMBL6654054 | 0.70 | HSD11B1 (0.56) | L3MBTL1HSD11B1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696234-B2 | Silver halide photosensitive material and isothiazolidine-3-one derivative | FUJI PHOTO FILM CO., LTD. (JP) | 2004-02-24 | — | — | US | disclosed |
| US-20030190566-A1 | Silver halide photosensitive material and isothiazolidine-3-one derivative | FUJI PHOTO FILM CO., LTD. | 2003-10-09 | — | — | US | disclosed |
| EP-0739338-B1 | SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE | UNIV WICHITA STATE (US) | 2002-04-10 | — | — | EP | disclosed |
| EP-0739338-A4 | NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE | UNIV WICHITA STATE (US) | 1997-03-26 | — | — | EP | disclosed |
| EP-0739338-A1 | NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE | THE WICHITA STATE UNIVERSITY (US) | 1996-10-30 | — | — | EP | disclosed |
| US-5550139-A | ANTIINFLAMMATORY AGENT, ANTITUMOR AGENT, ANTICARCINOGENIC AGENT | THE WICHITA STATE UNIVERSITY (US) | 1996-08-27 | — | — | US | disclosed |
| WO-1995018797-A1 | NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE | THE WICHITA STATE UNIVERSITY (US) | 1995-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030190566-A1 | Silver halide photosensitive material and isothiazolidine-3-one derivative | NRP1, NR2E3, SCN1B | L3MBTL1 1931/4885HSD11B1 2021/4885KMT2A 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.