Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472982 | 0.72 | HSD11B1 (0.38) | L3MBTL1HSD11B1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6536922 | 0.71 | L3MBTL1 (0.44) | L3MBTL1HSD11B1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7434618 | 0.71 | HSD11B1 (0.44) | L3MBTL1HSD11B1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8955444 | 0.69 | KMT2A (0.40) | L3MBTL1HSD11B1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7445271 | 0.68 | HSD11B1 (0.41) | L3MBTL1HSD11B1KMT2ANPC1ALDH1A1 | |
| SCHEMBL2883438 | 0.62 | NAAA (0.42) | — | |
| SCHEMBL2575844 | 0.59 | P2RX7 (0.46) | L3MBTL1HSD11B1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7421678 | 0.59 | L3MBTL1 (0.47) | L3MBTL1HSD11B1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8379405 | 0.59 | ALDH1A1 (0.57) | L3MBTL1HSD11B1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10435009 | 0.59 | DDB1 (0.38) | HSD11B1KMT2ANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550139-A | ANTIINFLAMMATORY AGENT, ANTITUMOR AGENT, ANTICARCINOGENIC AGENT | THE WICHITA STATE UNIVERSITY (US) | 1996-08-27 | — | — | US | disclosed |