SCHEMBL6537387

SCHEMBL6537387

NC(=O)N(c1ccccc1)S(=O)(=O)CCc1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
HTT P42858 2/20 0.44
PTGES2 Q9H7Z7 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
PLAAT3 P53816 1/20 0.41
PLAAT5 Q96KN8 1/20 0.41
PLAAT2 Q9NWW9 1/20 0.41
PLAAT4 Q9UL19 1/20 0.41
POLB P06746 1/20 0.40
MMP13 P45452 2/20 0.39
MMP3 P08254 1/20 0.39
MMP8 P22894 1/20 0.39
CNR1 P21554 2/20 0.39
EGFR P00533 1/20 0.39
ERBB2 P04626 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6321902 0.75 LMNA (0.54) MEN1KMT2ALMNAMAPTTAS2R14
SCHEMBL6469558 0.74 KDM4E (0.40) MEN1KMT2AHTTLMNAMAPT
SCHEMBL27521558 0.74 HSP90AA1 (0.59) MMP13MMP8SMN1; SMN2CA1CA2
SCHEMBL6463099 0.70 HSP90AA1 (0.49) LMNACA12CA1CA2CA9
SCHEMBL6468752 0.69 LTA4H (0.44) ALDH1A1
SCHEMBL30137226 0.69 AOC3 (0.48) MEN1KMT2AHTTPTGES2RAB9A
SCHEMBL8113147 0.68 KMT2A (0.43) KMT2ALMNAMAPTPOLBSMN1; SMN2
SCHEMBL2575447 0.68 KMT2A (0.47) KMT2ALMNAMAPTPOLBSMN1; SMN2
SCHEMBL27487172 0.68 KMT2A (0.43) MEN1KMT2AHTTLMNAMAPT
SCHEMBL6467727 0.68 HSP90AA1 (0.54) KMT2ALMNAMMP13MMP8SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US claimed
US-6740465-B2 MULTILAYER; TRANSPARENT SUPPORT; HEAT SENSITIVE ELEMENT AND RELEASE AGENT SIPIX IMAGING, INC. 2004-05-25 US disclosed
EP-1289768-A2 IMAGING MEDIA CONTAINING HEAT DEVELOPABLE PHOTOSENSITIVE MICROCAPSULES Sipix Imaging, Inc. (US) 2003-03-12 EP disclosed
US-20020155372-A1 Imaging media containing heat developable photosensitive microcapsules SIPIX IMAGING, INC. 2002-10-24 US disclosed
WO-2001092024-A2 IMAGING MEDIA CONTAINING HEAT DEVELOPABLE PHOTOSENSITIVE MICROCAPSULES SIPIX IMAGING, INC. (US) 2001-12-06 WO disclosed