Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PLG | P00747 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | KLK1 | P06870 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539256 | 0.80 | WDR5 (0.61) | WDR5LDHAALDH1A1HSD17B10KDM4E | |
| SCHEMBL3246521 | 0.79 | ALDH1A1 (0.46) | WDR5LDHAALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL63859 | 0.76 | CDC25B (0.57) | WDR5TDP1MAPTMEN1KMT2A | |
| SCHEMBL3282521 | 0.76 | WDR5 (0.47) | WDR5LDHAALDH1A1KDM4EGAA | |
| SCHEMBL6539923 | 0.75 | MAPT (0.49) | WDR5ALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL4938311 | 0.73 | CYP1A1 (0.46) | WDR5LDHAALDH1A1HSD17B10TSHR | |
| SCHEMBL3246612 | 0.73 | ALDH1A1 (0.46) | WDR5PLAUALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL3244528 | 0.73 | PTPN22 (0.54) | LDHAALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL1110593 | 0.73 | LDHA (0.60) | LDHAPLGKLK1ALDH1A1HSD17B10 | |
| SCHEMBL29435310 | 0.73 | ALDH1A1 (0.44) | WDR5LDHAF2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798295-B1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 2003-02-26 | — | — | EP | disclosed |
| US-5869501-A | PREVENTION AND/OR TREATMENT OF DISEASES CAUSED BY THROMBUS OR EMBOLUS. | YAMANOUCHI PHARMACEUTICAL CO. LTD (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0798295-A1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |