Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 6/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540455 | 0.85 | ALDH1A1 (0.50) | HTR2AKCNH2CA1CA2KMT2A | |
| SCHEMBL6553232 | 0.76 | HTR2A (0.51) | HTR2AKCNH2NAMPTCYP11B1CYP11B2 | |
| SCHEMBL6540607 | 0.75 | KDM4E (0.43) | KDM4EF13A1CYP11B1CYP11B2PLAAT3 | |
| SCHEMBL1437502 | 0.75 | KDM4E (0.69) | KDM4EF13A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL6552837 | 0.72 | CA2 (0.48) | HTR2AKCNH2CA1CA2CA12 | |
| SCHEMBL4440918 | 0.70 | NPC1 (0.58) | KDM4ENAMPTKMT2AALDH1A1 | |
| SCHEMBL3159145 | 0.69 | HTR2A (1.00) | HTR2AKCNH2KDM4ENAMPTCYP11B1 | |
| SCHEMBL17806453 | 0.68 | CA1 (0.71) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL6541334 | 0.68 | ALDH1A1 (0.57) | HTR2AKCNH2ALDH1A1 | |
| SCHEMBL2846480 | 0.67 | HPGDS (0.52) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | HTR2A 518/4885KCNH2 211/4885KDM4E 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.