Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540433 | 0.92 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRHPGDSMN1; SMN2 | |
| SCHEMBL6539344 | 0.91 | HPGD (0.42) | ALDH1A1LMNATSHRHPGDSMN1; SMN2 | |
| SCHEMBL6539405 | 0.88 | HPGD (0.49) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL6539318 | 0.87 | HPGD (0.47) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL6255678 | 0.87 | HPGD (0.43) | ALDH1A1LMNATSHRHPGDSMN1; SMN2 | |
| SCHEMBL6539699 | 0.83 | HPGD (0.43) | ALDH1A1LMNATSHRHPGDSMN1; SMN2 | |
| SCHEMBL6233246 | 0.82 | RAB9A (0.50) | ALDH1A1LMNATSHRHPGDSMN1; SMN2 | |
| SCHEMBL6539856 | 0.81 | MTNR1A (0.48) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL6252437 | 0.81 | MTNR1A (0.42) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL6539351 | 0.81 | RAB9A (0.53) | ALDH1A1LMNAHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | ALDH1A1 163/4885LMNA 2620/4885TSHR 4439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.