Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6539318 | 0.91 | HPGD (0.47) | HPGDSMN1; SMN2NPC1RAB9APTGS2 | |
| SCHEMBL6392729 | 0.89 | HPGD (0.46) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6540433 | 0.89 | ALDH1A1 (0.44) | HPGDSMN1; SMN2NPC1RAB9APTGS2 | |
| SCHEMBL6540475 | 0.88 | ALDH1A1 (0.44) | HPGDSMN1; SMN2NPC1RAB9APTGS2 | |
| SCHEMBL6233246 | 0.87 | RAB9A (0.50) | HPGDSMN1; SMN2NPC1RAB9APTGS2 | |
| SCHEMBL6255678 | 0.87 | HPGD (0.43) | HPGDSMN1; SMN2NPC1RAB9APTGS2 | |
| SCHEMBL6539351 | 0.86 | RAB9A (0.53) | HPGDSMN1; SMN2NPC1RAB9APTGS2 | |
| SCHEMBL6540484 | 0.86 | HPGD (0.41) | HPGDSMN1; SMN2NPC1RAB9APTGS2 | |
| SCHEMBL6539766 | 0.82 | IKBKB (0.46) | PTGS2ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6540413 | 0.81 | HPGD (0.44) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | HPGD 29/4885SMN1; SMN2 3341/4885NPC1 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.