Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539405 | 0.86 | HPGD (0.49) | HPGDSMN1; SMN2RAB9ANPC1PTGS2 | |
| Hydrochloric Acid SCHEMBL6539318 | 0.83 | HPGD (0.47) | HPGDSMN1; SMN2RAB9ANPC1PTGS2 | |
| SCHEMBL6540433 | 0.82 | ALDH1A1 (0.44) | HPGDSMN1; SMN2RAB9ANPC1PTGS2 | |
| SCHEMBL6538888 | 0.82 | PPARD (0.38) | HPGDSMN1; SMN2RAB9ANPC1PTGS2 | |
| SCHEMBL6539351 | 0.81 | RAB9A (0.53) | HPGDSMN1; SMN2RAB9ANPC1PTGS2 | |
| SCHEMBL6540475 | 0.80 | ALDH1A1 (0.44) | HPGDSMN1; SMN2RAB9ANPC1PTGS2 | |
| SCHEMBL6233246 | 0.80 | RAB9A (0.50) | HPGDSMN1; SMN2RAB9ANPC1PTGS2 | |
| SCHEMBL6255678 | 0.79 | HPGD (0.43) | HPGDSMN1; SMN2RAB9ANPC1PTGS2 | |
| SCHEMBL6392729 | 0.76 | HPGD (0.46) | HPGDSMN1; SMN2RAB9ANPC1PPARD | |
| SCHEMBL6256472 | 0.76 | PPARD (0.41) | PPARDPPARACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157891-A1 | Inhibitor of cox | PTGS1, PTGS2, PTGES2 | HPGD 29/4885SMN1; SMN2 3341/4885RAB9A 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.